منابع مشابه
Low-dose enoximone improves exercise capacity in chronic heart failure. Enoximone Study Group.
OBJECTIVES This study was designed to evaluate the effects of low-dose enoximone on exercise capacity. BACKGROUND At higher doses the phosphodiesterase inhibitor, enoximone, has been shown to increase exercise capacity and decrease symptoms in heart failure patients but also to increase mortality. The effects of lower doses of enoximone on exercise capacity and adverse events have not been ev...
متن کاملTreatment of severe heart failure: quantity or quality of life? A trial of enoximone. Enoximone Investigators.
OBJECTIVES To determine the effects of enoximone on mortality and quality of life in patients with severe end stage heart failure. DESIGN A randomised, double blind, placebo controlled trial of the addition of enoximone to conventional treatment. Planned minimum follow up of one year. SETTING District general hospitals and cardiological referral centres in the United Kingdom. PATIENTS Pla...
متن کاملchronic pain in chronic heart failure: a review article
heart failure (hf) is one of the main causes of death and disability in the world. the prevalence of hf in developed countries is between 1% and 2% of the adult population and approximately between 6% and 10% in the elderly, giving rise to high costs of care and treatment. indeed, in the united states, the direct and indirect costs exceeded 23 billion dollars in 2002. hf is typically character...
متن کاملDouble-blind crossover comparison of enoximone and placebo in patients with congestive heart failure.
The efficacy of oral enoximone, a new positive inotropic and vasodilator agent, was assessed in 12 patients with chronic congestive heart failure (New York Heart Association [NYHA] class II or III) in a double-blind randomized crossover comparison with placebo. Duration of each treatment was 6 weeks and the dose of enoximone was 150 mg tid. Efficacy was assessed by exercise tolerance, symptoms,...
متن کاملChronic Heart Failure in Congenital Heart Disease
770 Part I: General Considerations Introduction The past 60 years have brought remarkable advancements in the diagnosis and treatment of congenital heart disease (CHD). Early diagnosis and improvements in cardiac surgery and interventional cardiology have resulted in unprecedented survival of patients with CHD, even those with the most complex lesions. Despite remarkable success in treatments, ...
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ژورنال
عنوان ژورنال: Circulation
سال: 1990
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.82.3.1049